Breast Cancer

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Can Some Breast Cancer Tumors Regress if Left Untreated?

November 24, 2008

Little is known about how untreated breast cancer grows, because it would be considered unethical to not treat women with breast tumors. However, some types of cancer, such as metastatic melanoma, have been known to spontaneously regress or shrink on their own. And there have been about 32 reported cases of invasive breast cancer that have spontaneously regressed.

Could there be some type of breast tumor, as yet unknown, that’s unlikely to grow rapidly and threaten a patient’s life? Maybe, but many doctors remain skeptical.

There are reasons the study numbers don’t match, they say, including that women in the second group only had one mammogram, and there may have been more cases of cancer than were detected. Or use of hormone therapy may have differed between the two groups.

“The authors try to dismiss some of the reasons why those two numbers might not be equal and they latch on to what I think is one of the more far-fetched explanations—that a large fraction of these tumors have regressed,” says Chris Kagay, MD, a clinical fellow at Harvard School of Medicine. “The authors are making a bold proposition about the natural history of breast cancer based on pretty limited evidence.”

There’s little scientific evidence that breast cancers can regress, adds Robert A. Smith, PhD, director of Cancer Screening at the American Cancer Society. “The conclusion that more than 1 in 5 invasive breast cancers is destined to regress without incident if not detected by mammography is nothing more than an overreaching leap in logic.”

The study is also missing some important information—mortality data. Women who have routine mammograms should be less likely to die of breast cancer than women who do not have them. A follow-up study examining death rates could either confirm or dismiss the study, experts say.

“Now we’re left in this odd position of having this intriguing finding but not knowing where to go with it,” says Kaplan. “It’s important to understand that this is a pretty preliminary finding. It’s at odds with what most people believe.”

Cancer specialists worry that this type of research can be dangerous if it discourages women from having mammograms.

“It’s important to remember that mammography saves lives,” says Dr. Kagay. “Suggesting that screening is not valuable or that these cancers detected will spontaneously regress is quite frankly dangerous if it convinces women that they don’t need to be screened.”


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Comments (15)

The following content represents the opinions of Health.com users. It is not editorially reviewed for medical or factual accuracy. It does not constitute medical advice. See your doctor for medical advice.
  • Eric

    Great, now Health Insurance will stop covering breast cancer.

  • mhepburn

    This is what I have instinctively felt for years. I am suspicious of the many discoveries of breast cancer, and resulting treatments that may not be necessary.

  • Jerlyn

    I hope you were being sarcastic *Eric* because women always tend to have more medical things to cover. I doubt they will quit covering breast cancer.

    Anyway – back to the article I am not surprised that it goes away, there’s different effects by different cancers for different people. According to studies they realized that, cancer doesn’t necessarily affect your body the same as someone else with the same type.

  • pheelion

    I, for many years, have wondered if this might not be the case with all or many cancers.

  • lisa

    I no I have breast Cancsr I am 38 All the members Of my Family have had what ever cancer you can imange. My breast tell me somethings wrong I have no insurance. And I am am scared to no the truth. I fell it,s god that wants me to go threw this. I don,t no what to do. I do no everone in my family that has had cancer has died because they let the doctoors take over before the age of 50 except my grandma that died at age 70 and was ate up with it threw out her body, she never let the doctors touch her. her three daughters died before 50 because they did I believe that. what do i do?

  • I have had breast cancer, and have been around lots of people with cancer. Some have amazing stories.

  • Ann

    I have cyst on my left overy and breast. Will they regress on their own or should I have them treated? Thank you

  • PROFESSOR SHIRLEY

    I HAD BREAST CANSER TWICE.WAS TOLD THAT I HAD 3MONTHS TO LIVE. THAT WAS 35 YEARS AGO. COUNTY HOSPITAL WILL TAKE YOUR CASE.WITHOUT PAYMENT. THE SURVIVAL RATE NOW IS MUCH HIGER THAN WHEN YOUR MOTHER HAD IT I AM WORRIED ABOUT YOU AND I MORE TO SAY THAT CAN HELP YOU . MY EMAIL IS SKRAUTHAMER@yahoo.com.WRITE ME NOW. MY PROFESSORSHIP IS IN PSYCH AND I WOULD LIKE TO DISCUSS THIS WITH FURTHER.

  • PROFESSOR SHIRLEY

    LISA —–THE ABOVE LETTER IS FOR YOU

  • Denise

    I seriously doubt that Shirly is a professor of any type since almost every other word in her entry was misspelled.. Please don’t take a serious matter like cancer and give someone advice when you’re not even capable of spelling. thats sad!

  • Angel

    I would definitely caution anyone against trying this (leaving the cancer untreated in the hopes it will go away).

    My dear aunt found a lump in her breast 3 years ago when she was 50…anyhow for reasons unbeknownst to the rest of us she decided to leave it untreated, hoping it would go away, and shunning conventional medicine and surgery- she truly believed God would give her a miracle. The rest of us sat back in disbelief, shock and anger as her tumor continued to grow- eventually it was evident for all to see- like a watermelon under her shirt. She never even had it staged. It could have been benign for all we know but it grew so large it broke blood vessels.

    Anyhow, she died one week ago today. It just all seemed so unnecessary which is what makes her death difficult to bear.

    Please, if you find a lump, seek treatment.

  • katbur

    As a breast cancer survivor who was diagnosed at age 38 with no family history this “research” has infuriated me. If you find a lump get it checked. There is always the possibility that it could regress on it’s own but are you willing to risk your very life to find out if yours is that one? Please….see your doctor ladies. My blog has lots of breast cancer research on it if you want some other information. http://aftercancernowwhat.blogspot.com

  • Linda

    Think about it…breast cancer used to be fatal much more than now. There are many women now alive years after breast cancer diagnosis because we now have the means to detect it earlier and more advanced treatment. If I had a tumor, I certainly wouldn’t risk my life HOPING it would regress. I would get treatment; the sooner the better. When I studied Statistics, one thing I learned is that statistics can be misleading, because sometimes only part of the equation is presented. The quoted information does not impress me. A LOT more information needs to be added before there is any reason to believe this. Do not risk your life based on incomplete research!

  • Anne Menze

    Dianosed with breast cancer this summer. Choose no treatment. Alredy coping with pain 24/7 with back and leg issues. Mobility down to 25% and a Senior person. Choose not to live my remaining days in more recouperation. God Bless

  • DLT

    Look at the positive, remain clear in truth.

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