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Chromosome Linked to Diabetics’ Heart Risks

November 26, 2008

TUESDAY, Nov. 25 (HealthDay News) — Adding to earlier research, a new study has identified a genetic variation that increases the risk of coronary artery disease (CAD) in type 2 diabetes patients with poor sugar glucose (glycemic) control.

Previous research has found that genetic variations on a genetic chromosome known as chromosome 9p21 are associated with increased risk of CAD in the general population. Read More


Diabetics Spend Thousands More on Care

November 25, 2008

TUESDAY, Nov. 25 (HealthDay News) — People with diabetes spend thousands of dollars more on medical costs each year than those without the disease, and that disparity increases substantially each year after the initial diabetes diagnosis.

That’s the finding of a new study by researchers at RTI International, a nonprofit research institute in North Carolina.

The researchers calculated that a 50-year-old newly diagnosed diabetes patient spends $4,174 more on medical care a year than someone the same age without diabetes. For that diabetes patient, medical costs increase $158 a year every year after they’re diagnosed and that doesn’t include increased medical costs due to aging. Read More


Avandia’s Heart Risk Higher Than Others in Its Class

November 25, 2008

MONDAY, Nov. 24 (HealthDay News) — The widely used diabetes drug Avandia — already controversial because of cardiovascular side effects — may be riskier than Actos, another drug in the same class, researchers reported Monday.

The risk of heart failure and death for older diabetics appears greater with Avandia (rosiglitazone) than with Actos (pioglitazone), both of which are part of a class of drugs called thiazolidinediones, Harvard University researchers said. Read More


Genes Only Slightly Helpful For Predicting Diabetes

November 19, 2008
diabetes-dna

Istockphoto
By Anne Harding

WEDNESDAY, Nov. 19, 2008 (Health.com) — About 11 to 18 genes can help predict a person’s likelihood of developing type 2 diabetes, two new studies say. However, those genes don’t add much more to a patient’s diabetes-risk profile than information that’s easily available, such as body mass index, family history, and lifestyle, according to the studies in the New England Journal of Medicine.

The studies included more than 20,000 men and women who were followed for 20 to 30 years to see if they developed diabetes. In both studies, the gene variants’ predictive effect was more powerful for younger people. Read More


Blood Sugar Control Helps Diabetics Preserve Sight

November 17, 2008

FRIDAY, Nov. 14 (HealthDay News) — Maintaining good control over one’s blood sugar levels can help people with type 1 diabetes better avoid retinopathy, a serious disorder that damages the eye’s retina, researchers say.

The findings come from a 25-year study that confirms prior large studies. The findings were published in the November issue of Ophthalmology.

The Wisconsin Epidemiologic Study of Diabetic Retinopathy also found that being male, having higher blood pressure, having protein in urine (a manifestation of diabetic kidney disease) and a greater body mass index also increased one’s risk of developing diabetic retinopathy. Read More


Coated Stents Best for Heart Patients With Diabetes

November 11, 2008

MONDAY, Nov. 10 (HealthDay News) — Drug-coated stents appear to be superior to bare metal stents in both efficacy and safety in patients with diabetes, new research shows.

“I would say consistently from randomized trials that there is clear efficacy and clear reduction for repeat revascularization procedures [with drug-coated stents],” said senior study author Dr. Laura Mauri, an assistant professor of medicine at Brigham and Women’s Hospital and Harvard Medical School. “That is now also augmented by the fact that there is excellent safety in patients who have a similar ability to take dual antiplatelet therapy.” Read More


Aspirin Doesn’t Guard Diabetics Against Heart Disease

November 10, 2008

SUNDAY, Nov. 9 (HealthDay News) — Two large studies released Sunday cast doubt on the cardiac benefits of either low-dose aspirin or vitamin supplements.

First, Japanese researchers found that low-dose aspirin did not reduce the risk of cardiovascular events in people with type 2 diabetes.

Second, Harvard researchers concluded that neither vitamin E nor vitamin C reduced the risk of major cardiovascular events in a group of low-risk, middle-aged male physicians. Read More


Too Few Americans Aware of ‘Pre-Diabetes’

November 7, 2008

THURSDAY, Nov. 6 (HealthDay News) — Too many American adults are unaware of “pre-diabetes” and not enough take action to reduce their risk, according to a U.S. Centers for Disease Control and Prevention study released Thursday.

People with pre-diabetes — a condition in which blood glucose levels are higher than normal but not high enough to be classified as diabetes — are at increased risk for developing type 2 diabetes, heart disease and stroke. But lifestyle changes such as diet and exercise can prevent or delay development of diabetes and its complications. Read More


Hormone Lowers Glucose Levels in Mice

November 5, 2008

TUESDAY, Nov. 4 (HealthDay News) — A hormone produced by fat tissues holds promise for people with insulin resistance or type 2 diabetes, a new report suggests.

The hormone, called apelin, significantly lowered blood sugar levels when injected intravenously into normal and obese mice, according to a study published in the November issue of the journal Cell Metabolism. Apelin also appeared to restore glucose tolerance and improve glucose uptake in mice that are obese and insulin resistant. Read More


Fish Twice a Week Cuts Diabetics’ Kidney Risks

November 4, 2008

MONDAY, Nov. 3 (HealthDay News) — Eating fish twice a week may help reduce the risk of kidney disease in people with diabetes, according to a British study of more than 22,000 adults, including 517 with diabetes.

The participants’ fish consumption was determined using dietary and lifestyle questionnaires. People with diabetes who ate less than one serving of fish per week were about four times more likely (18 percent) to have protein in their urine than those who ate at least two servings of fish per week (4 percent). Read More




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