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Drug Used to Enhance Memory May Be Addictive

March 17, 2009

People who have no medical need for this medication should think twice about taking it to enhance their mental performance, Dr. Volkow says. While not everyone who uses it will become addicted, she explains, some people may be vulnerable. Right now the relatively high cost of Provigil has limited its recreational use, she says, but when the drug comes off patent in 2012 and cheaper generic versions become available, any abuse and addiction potential is likely to be revealed. Provigil costs about $10 for a 200 mg dose, although the price can vary.

“There are individuals that will become addicted when they become exposed to stimulants,” Dr. Volkow says. “Time will tell whether the same is true for modafinil.”

Jeffry Vaught, PhD, notes that when the drug was approved over a decade ago, its label warned that it had the potential to be abused and suggested doctors monitor patients carefully if they have a history of drug abuse. “It’s been that way since the beginning,” says Vaught, the chief scientific officer and executive vice president at Cephalon, Inc., which makes Provigil.

The company has been checking for signs that the drug is being abused, says Vaught, but “we’ve just not picked up any signals that there’s any abuse liability that would cause us concern.”

He notes that the drug is currently being studied as a treatment for methamphetamine and cocaine addiction and “generally you do that with a substance that’s considerably less to non abuseable.” It’s also being studied as a treatment for bipolar disorder.

Vaught says the company does not condone the use of the drug for enhancing mental performance. “I would also state from a scientific perspective that there’s limited to no data to suggest there’s any cognitive benefit in normal individuals,” he says.


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Comments (8)

The following content represents the opinions of Health.com users. It is not editorially reviewed for medical or factual accuracy. It does not constitute medical advice. See your doctor for medical advice.
  • Franz

    I wonder if schools would address memory enhancing techniques like mnemonics if youths would fall for drugs so easily …

  • Kim Cole

    I would like a list of natural remedies for A.D.H.D.i.e….. Supplements, foods to avoid and foods that would benefit.
    Sincerley, Kim Cole

  • kelle

    Wow. I ceases to amaze me that people still dont understand how addictive and harmful many of these drugs are. Of course they are ADDICTIVE!! Yet so many children are on them. What happens when all of these kids grow up? Will they be on meds the rest of their natural life. It appears so as now the big pharms are marketing these stimulants to adults as well. SCARY.

  • rvrrtzz1

    KIM COLE,
    THE ONLY FOOODS THAT AGGREVATE ADHD IS RED DYES SUCH AS CHERRY KOOL-AID. ALSO MSG IS FOUND IN MANY SPICES WE COOK WITH. ALONG WITH VERY CONSISTANT STRUCTURED ENVIRONMENT. IT IS IMPORTANT TO NOT CHANGE YOUR ROUTINE BECAUSE IT THROWS EVERYTHING OFF BALANCE AND YOU HAVE TO START OVER GETTING BACK YOUR STRUCTURED ROUTINE. YOU GET UP AT THE SAME TIME, HAVE BREAKFAST AT CERTAIN TIME, LUNCH AT NOON, ETC. STAY ON SCHEDUEL BEST YOU CAN AND YOU WILL FIND YOU CAN ACTUALL HAVE PEACE DURNG THE DAY WITHOUT CAOS.CAFFEEN WILL HELP CALM DOWN AN ADHD PERSON. MY DAUGHTER CAN DRINK CAPPICINO AND GO RIGHT OFF TO SLEEP. NO KIDDING. GOOD LUCK
    KAREN

  • hotlilangel

    i think any drug can be addictive. It depends on the dose tho

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