Placebo Acupuncture Tied to Higher IVF Pregnancies

THURSDAY, Nov. 13 (HealthDay News) — Compared to real acupuncture, placebo acupuncture was associated with significantly higher overall pregnancy rates among women undergoing in-vitro fertilization (IVF), says a University of Hong Kong study.

In real acupuncture, fine needles are inserted into particular points on the body. In placebo acupuncture, blunt needles that look identical to real acupuncture needles retract into the handle of the needle when pressed on the skin, but still give the sensation and appearance of entering the skin.

The researchers gave real or placebo acupuncture to 370 women on the day of embryo transfer and found that 55.1 percent of those who received placebo acupuncture became pregnant, compared to 43.8 percent of those who received real acupuncture. The findings were published in the Nov. 13 issue of Human Reproduction.

“We found a significantly higher overall pregnancy rate following placebo acupuncture when compared with that of real acupuncture,” study author Dr. Ernest Hung Yu Ng, an associate professor in the department of obstetrics and gynecology, said in a European Society for Human Reproduction and Embryology news release. “In addition, there was a trend towards higher rates of clinical pregnancy, ongoing pregnancy, live birth and embryo implantation in the placebo acupuncture group, although the differences did not reach statistical significance.”

The results suggest that placebo acupuncture may not act as an inert control for real acupuncture and may be having a real effect. That theory is supported by the fact that the researchers noted significant changes in measurements for uterus receptivity and patient stress levels after the women received both the real and placebo acupuncture.

There are two possible explanations for the study results.

“Placebo acupuncture is similar to acupressure and therefore is good enough to improve the pregnancy rate,” said Ng, who added it’s also possible that real acupuncture may, in some way, reduce the pregnancy rate.

“So far, there is no evidence that real acupuncture would adversely affect IVF outcomes because, in a previous meta-analysis of several acupuncture studies, the pregnancy rate was higher in the acupuncture group than in the control group. However, we cannot draw a firm conclusion about this from our current study, as we did not compare the two groups with a third control group of patients who received neither form of acupuncture. Further studies should be conducted to compare placebo or noninvasive acupuncture and controls without acupuncture,” Ng said.

More information

The U.S. National Center for Complementary and Alternative Medicine has more about acupuncture.